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Peripheral Neuropathy vs Radiculopathy

September 28, 2022

Radiculopathy can lead to sharp pains throughout the body, numbness, weakness or loss of reflexes. Although these symptoms are similar to those of peripheral neuropathy, it’s important to know the difference between the two.

Peripheral Neuropathy vs Radiculopathy

Both peripheral neuropathy and radiculopathy affect the nerves, but in different ways. Peripheral neuropathy refers to the damage or dysfunction of nerves outside the central nervous system, or your brain and spinal cord.  Peripheral neuropathy usually is a problem stemming from the nerve itself, either due to nutritional issues, systemic disorders or immune dysfunction.  

Rather than affecting your peripheral nerves, radiculopathy occurs when your nerves are pinched at their root. Nerve roots split off from your spinal cord in order to reach the various parts of your body. These nerve roots can become pinched or damaged, resulting in pain and discomfort. 

The lower back is the most common area affected by radiculopathy, in particular the sciatic nerve. 

When a nerve root is pinched, it can be an unpleasant experience, although symptoms can vary depending on the location of the pinched nerve.

Scared To Visit An Orthopedic Specialist: Muscle Pain Might Not Be What You Think

What Causes Radiculopathy?

Radiculopathy is typically the result of a change in the tissue surrounding the spine, which leads to compression of the openings, or foramen, where nerve roots go in and out of the spine. This is known as foraminal stenosis.  This is typically caused by spinal degeneration as the aperture for the nerve root becomes smaller due to slow-growing osteophytes, ligament thickening and synovial hypertrophy.  

Although less common, radiculopathy can also be the result of spinal infections or growths that press against nerve roots.  Sometimes a herniated disc in the spinal cord is actually large enough to compress an existing nerve root.  Many physicians believe this is best diagnosed with a nerve conduction study. 

Pain Relief Options

It’s important to consult with your treating physician to determine whether or not the cause of your discomfort or pain is in fact, radiculopathy. If it is radiculopathy that is causing your symptoms, this will help you and your physician work toward a treatment plan.  Radiculopathy might coexist with peripheral neuropathy and it is important to recognize this possibility.  

Taking supplements like Alpha-Lipoic Acid (ALA), that reduce inflammation and pain can be beneficial. ALA also promotes healthy nerve function. Omega-3 is also a beneficial supplement for reducing overall systemic inflammation.  In some cases, radiculopathy requires surgical care or targetted injections. If you believe you have radiculopathy, or any other nerve-related condition, contact Warner Orthopedics and Wellness to schedule an appointment.

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Dr. Warner has always been dedicated to delivering expert care to her patients. Her team of providers extends her reach, bringing her knowledge and expertise to more patients across the Greater Baton Rouge community. With a compassionate approach to orthopedic care, they treat each patient as a whole person—not just a case number or a set of symptoms.


Find out from Dr. Warner’s hand-picked team how you can improve your function and optimize your wellness.

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    If you are not a patient of Dr. Meredith Warner, please note that the information provided is for educational and informational purposes only. It is not intended as, nor should it be construed as, medical advice, diagnosis, or treatment. Dr. Warner is not establishing a physician-patient relationship by responding to questions or providing content. Always consult your own healthcare provider or physician before making any changes to your health or medical regimen.
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